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1

ChemInform Abstract: Reaction of Some 1,2-Diaza-1,3-butadienes with Activated Methine Compounds. A Straightforward Entry to 1,4-Diyhdropyridazine, Pyridazine, and 4,5(4H,5H)-Cyclopropylpyrazole Derivatives.

Orazio A. Attanasi, Paolino Filippone, Chiara Fiorucci, Elisabetta Foresti, Fabio Mantellini

Journal:

Year:

1999

Language:

english

File:

PDF, 41 KB

english, 1999

2

ChemInform Abstract: Aspects of the Chemistry of Functionalized 1-Phenylpyrazoles Available from 1,2-Diaza-1,3-butadienes and 2-Phenylazo-1,3-dicarbonyl Compounds.

Orazio A. Attanasi, Paolino Filippone, Chiara Fiorucci, Fabio Mantellini

Journal:

Year:

1999

File:

PDF, 31 KB

1999

3

ChemInform Abstract: A New and Efficient Synthesis of ortho- and para-Benzoquinones of Cardanol Derivatives by the Catalytic System MeReO3—H2O2.

Raffaele Saladino, Veronica Neri, Enrico Mincione, Stefano Marini, Massimiliano Coletta, Chiara Fiorucci, Paolino Filippone

Journal:

Year:

2000

File:

PDF, 34 KB

2000

4

ChemInform Abstract: Reaction Between Conjugated Azoalkenes and Pyrazolinones: A Precious Entry to New Conjugated Azodiene and Asymmetric 4,4′-Bipyrazole Derivatives.

Orazio A. Attanasi, Paolino Filippone, Chiara Fiorucci, Fabio Mantellini

Journal:

Year:

2001

File:

PDF, 30 KB

2001

5

Reaction of thiocarboxylic acids with conjugated azoalkenes

Orazio A. Attanasi, Simonetta Buratti, Paolino Filippone, Chiara Fiorucci, Elisabetta Foresti, Daniela Giovagnoli

Journal:

Year:

1996

Language:

english

File:

PDF, 1.09 MB

english, 1996

6

Synthesis and reactions of some nitrone derivatives

Orazio A Attanasi, Paolino Filippone, Chiara Fiorucci

Journal:

Year:

1997

Language:

english

File:

PDF, 695 KB

english, 1997

7

1-Amino-2-chloromethylene-2,3-dihydropyrroles by unusual reaction of conjugated azoalkenes with 2-chloro-1,3-dicarbonyl compounds

Orazio A Attanasi, Paolino Filippone, Chiara Fiorucci, Fabio Mantellini

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

8

Aspects of the chemistry of functionalized 1-phenylpyrazoles available from 1,2-diaza-1,3-butadienes and 2-phenylazo-1,3-dicarbonyl compounds

Orazio A Attanasi, Paolino Fïlippone, Chiara Fïorucci, Fabio Mantellini

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 233 KB

english, 1999

9

Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis

Luigina Graziosi, Andrea Mencarelli, Chiara Santorelli, Barbara Renga, Sabrina Cipriani, Emanuel Cavazzoni, Giuseppe Palladino, Stefan Laufer, Michael Burnet, Annibale Donini, Stefano Fiorucci

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

10

Absolute rate constants for the reaction of peroxyl radicals with cardanol derivatives

Amorati, Riccardo, Pedulli, Gian Franco, Valgimigli, Luca, Attanasi, Orazio A., Filippone, Paolino, Fiorucci, Chiara, Saladino, Raffaele

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

2001

Language:

english

File:

PDF, 141 KB

english, 2001

11

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Angela Zampella, Maria Chiara Monti, Eleonora Distrutti, Stefano Fiorucci

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 846 KB

english, 2011

12

Reaction of Some 1,2-Diaza-1,3-butadienes with Activated Methine Compounds. A Straightforward Entry to 1,4-Dihydropyridazine, Pyridazine, and 4,5(4 H ,5 H )-Cyclopropylpyrazole Derivatives

Attanasi, Orazio A., Filippone, Paolino, Fiorucci, Chiara, Foresti, Elisabetta, Mantellini, Fabio

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 136 KB

english, 1998

13

Epigenetic Modulation by Methionine Deficiency Attenuates the Potential for Gastric Cancer Cell Dissemination

Luigina Graziosi, Andrea Mencarelli, Barbara Renga, Claudio D’Amore, Angela Bruno, Chiara Santorelli, Emanuel Cavazzoni, Francesco Cantarella, Emanuele Rosati, Annibale Donini, Stefano Fiorucci

Journal:

Journal of Gastrointestinal Surgery

Year:

2013

Language:

english

File:

PDF, 440 KB

english, 2013

14

Manganese and iron tetraphenylporphyrin-catalyzed oxidation of a cardanol derivative (hydrogenated tert -butylcardanol)

Tagliatesta, Pietro, Crestini, Claudia, Saladino, Raffaele, Neri, Veronica, Filippone, Paolino, Fiorucci, Chiara, Attanasi, Orazio A.

Journal:

Journal of Porphyrins and Phthalocyanines

Year:

2002

Language:

english

File:

PDF, 204 KB

english, 2002

15

A new and efficient synthesis of ortho- and para-benzoquinones of cardanol derivatives by the catalytic system MeReO3–H2O2

Saladino, Raffaele, Neri, Veronica, Mincione, Enrico, Marini, Stefano, Coletta, Massimiliano, Fiorucci, Chiara, Filippone, Paolino

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 141 KB

english, 2000

16

Su2132 Dissociation of Activity of Ileal and Liver FXR Mediates Metabolic Effects in a Rodent Model of Bariatric Surgery.

Mencarelli, Andrea, Santorelli, Chiara, Graziosi, Luigina, D'Amore, Claudio, Renga, Barbara, Cipriani, Sabrina, Distrutti, Eleonora, Donini, Annibale, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 159 KB

english, 2013

17

1009 Epigenetic Modulation of Adhesion and Proliferation Pathways by Methionine Deficiency Attenuates Potential for Dissemination of Gastric Cancer Cells

Graziosi, Luigina, Mencarelli, Andrea, Renga, Barbara, Cavazzoni, Emanuel, Bruno, Angela, Santorelli, Chiara, Rosati, Emanuele, Fiorucci, Stefano, Donini, Annibale

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 52 KB

english, 2012

18

Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors

D’Amore, Claudio, Di Leva, Francesco Saverio, Sepe, Valentina, Renga, Barbara, Del Gaudio, Chiara, D’Auria, Maria Valeria, Zampella, Angela, Fiorucci, Stefano, Limongelli, Vittorio

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 755 KB

english, 2014

19

Variable-Gradient Generator for Micro- and Nano-HPLC

Cappiello, Achille, Famiglini, Giorgio, Fiorucci, Chiara, Mangani, Filippo, Palma, Pierangela, Siviero, Antonella

Journal:

Analytical Chemistry

Year:

2003

Language:

english

File:

PDF, 127 KB

english, 2003

20

Exploitation of Cholane Scaffold for the Discovery of Potent and Selective Farnesoid X Receptor (FXR) and G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) Ligands

Festa, Carmen, Renga, Barbara, D’Amore, Claudio, Sepe, Valentina, Finamore, Claudia, De Marino, Simona, Carino, Adriana, Cipriani, Sabrina, Monti, Maria Chiara, Zampella, Angela, Fiorucci, Stefano

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

21

Heat shock proteins as key biological targets of the marine natural cyclopeptide perthamide C

Margarucci, Luigi, Monti, Maria Chiara, Mencarelli, Andrea, Cassiano, Chiara, Fiorucci, Stefano, Riccio, Raffaele, Zampella, Angela, Casapullo, Agostino

Journal:

Molecular BioSystems

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

22

Glucocorticoid-Induced Leucine Zipper (GILZ) Controls Inflammation and Tissue Damage after Spinal Cord Injury

Mazzon, Emanuela, Bruscoli, Stefano, Galuppo, Maria, Biagioli, Michele, Sorcini, Daniele, Bereshchenko, Oxana, Fiorucci, Chiara, Migliorati, Graziella, Bramanti, Placido, Riccardi, Carlo

Journal:

CNS Neuroscience & Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

23

Cystathionine γ-lyase, a H 2 S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids

Renga, Barbara, Bucci, Mariarosaria, Cipriani, Sabrina, Carino, Adriana, Monti, Maria Chiara, Zampella, Angela, Gargiulo, Antonella, d'Emmanuele di Villa Bianca, Roberta, Distrutti, Eleonora, Fiorucci

Journal:

AJP Heart and Circulatory Physiology

Year:

2015

Language:

english

File:

PDF, 870 KB

english, 2015

24

Novel and Convenient Synthesis of 1,4-Dihydropyridazines and Pyridazines from Aminocarbonylazoalkenes

Attanasi, Orazio, Filippone, Paolino, Fiorucci, Chiara, Mantellini, Fabio

Journal:

Year:

1997

File:

PDF, 196 KB

1997

25

Structure–function relationships in human cytochrome c: The role of tyrosine 67

Tognaccini, Lorenzo, Ciaccio, Chiara, D'Oria, Valentina, Cervelli, Manuela, Howes, Barry D., Coletta, Massimo, Mariottini, Paolo, Smulevich, Giulietta, Fiorucci, Laura

Journal:

Journal of Inorganic Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

26

Ethmoidal Encephalocele Associated With Cerebrospinal Fluid Fistula

Fraioli, Mario Francesco, Umana, Giuseppe Emanuele, Fiorucci, Giulia, Fraioli, Chiara

Journal:

Journal of Craniofacial Surgery

Year:

2014

Language:

english

File:

PDF, 636 KB

english, 2014

27

Reaction between Conjugated Azoalkenes and Pyrazolinones: A Precious Entry to New Conjugated Azodiene and Asymmetric 4,4′-Bipyrazole Derivatives

Attanasi, Orazio A., Filippone, Paolino, Fiorucci, Chiara, Mantellini, Fabio

Journal:

Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 275 KB

english, 2000

28

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Finamore, Claudia, Festa, Carmen, Renga, Barbara, Sepe, Valentina, Carino, Adriana, Masullo, Dario, Biagioli, Michele, Marchianò, Silvia, Capolupo, Angela, Monti, Maria Chiara, Fiorucci, Stefano, Zamp

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

29

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Sepe, Valentina, Festa, Carmen, Renga, Barbara, Carino, Adriana, Cipriani, Sabrina, Finamore, Claudia, Masullo, Dario, del Gaudio, Federica, Monti, Maria Chiara, Fiorucci, Stefano, Zampella, Angela

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

30

The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket

Ciaccio, Chiara, Tognaccini, Lorenzo, Battista, Theo, Cervelli, Manuela, Howes, Barry D., Santucci, Roberto, Coletta, Massimo, Mariottini, Paolo, Smulevich, Giulietta, Fiorucci, Laura

Journal:

Journal of Inorganic Biochemistry

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

31

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis

Carino, Adriana, Cipriani, Sabrina, Marchianò, Silvia, Biagioli, Michele, Santorelli, Chiara, Donini, Annibale, Zampella, Angela, Monti, Maria Chiara, Fiorucci, Stefano

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.75 MB

english, 2017

32

Case History: a 5-km long waterborne geophysical survey along the Po river within the city of Turin (NW Italy)

Sambuelli, Luigi, Fiorucci, Adriano, Dabove, Paolo, Pascal, Ivan, Colombero, Chiara, Comina, Cesare

Journal:

Year:

2017

Language:

english

File:

PDF, 4.43 MB

english, 2017

33

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice

Carino, Adriana, Cipriani, Sabrina, Marchianò, Silvia, Biagioli, Michele, Scarpelli, Paolo, Zampella, Angela, Monti, Maria Chiara, Fiorucci, Stefano

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 6.26 MB

english, 2017

34

Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases

Biagioli, Michele, Mencarelli, Andrea, Carino, Adriana, Cipriani, Sabrina, Marchianò, Silvia, Fiorucci, Chiara, Donini, Annibale, Graziosi, Luigina, Baldelli, Franco, Distrutti, Eleonora, Costantino,

Journal:

Inflammatory Bowel Diseases

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

35

Su1053 - Bar704, a Potent and Selective Fxr Agonist Protects Against Intestinal Fibrosis

Fiorucci, Chiara, Carino, Adriana, Biagioli, Michele, Marchianò, Silvia, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 234 KB

english, 2018

36

241 - GPBAR1 (TGR5) is a Modulator of Liver Immunity and Reverses Liver Inflammation in a Mouse Models of Acute Hepatitis

Biagioli, Michele, Carino, Adriana, Fiorucci, Chiara, Marchianò, Silvia, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 147 KB

english, 2018

37

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

Cipriani, Sabrina, Renga, Barbara, D’Amore, Claudio, Simonetti, Michele, De Tursi, Antonio Angelo, Carino, Adriana, Monti, Maria Chiara, Sepe, Valentina, Zampella, Angela, Fiorucci, Stefano, Zhang, Ya

Journal:

Year:

2015

Language:

english

File:

PDF, 5.47 MB

english, 2015

38

2 - GPBAR1 (TGR5) Agonism Reverses Endothelial Dysfunction and Liver Injury in a Dietetic Model of Steatohepatitis

Carino, Adriana, Marchianò, Silvia, Biagioli, Michele, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano, Fiorucci, Chiara

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 603 KB

english, 2018

39

Tu1738 - The Aryl Hydrocarbon Receptor Mediates Anti-Inflammatory Activities of Natural and Synthetic Pelargonidines in Mouse Models of Colitis

Carino, Adriana, Biagioli, Michele, Marchianò, Silvia, Distrutti, Eleonora, Fiorucci, Chiara, Annunziato, Giannamaria, Costantino, Gabriele, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 307 KB

english, 2018

40

Tu1748 - Probiotics Beyond Taxonomy: Evidence that Anti-inflammatory Properties of Live Biotherapeutic Products Require Phenotypic Characterization

Biagioli, Michele, Fiorucci, Chiara, Carino, Adriana, Marchianò, Silvia, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 608 KB

english, 2018

41

Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis

Carino, Adriana, Marchianò, Silvia, Biagioli, Michele, Bucci, Mariarosaria, Vellecco, Valentina, Brancaleone, Vincenzo, Fiorucci, Chiara, Zampella, Angela, Monti, Maria Chiara, Distrutti, Eleonora, Fi

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 2.32 MB

english, 2018

42

Novel isoxazole derivatives with potent FXR agonistic activity prevent acetaminophen induced liver injury

Sepe, Valentina, Marchianò, Silvia, Finamore, Claudia, Baronissi, Giuliana, Di Leva, Francesco Saverio, Carino, Adriana, Biagioli, Michele, Fiorucci, Chiara, Cassiano, Chiara, Monti, Maria Chiara, Del

Journal:

ACS Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 484 KB

english, 2018

43

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1

Di Leva, Francesco Saverio, Festa, Carmen, Carino, Adriana, De Marino, Simona, Marchianò, Silvia, Di Marino, Daniele, Finamore, Claudia, Monti, Maria Chiara, Zampella, Angela, Fiorucci, Stefano, Limon

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.39 MB

english, 2019

44

Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH

Carino, Adriana, Biagioli, Michele, Marchianò, Silvia, Fiorucci, Chiara, Zampella, Angela, Monti, Maria Chiara, Scarpelli, Paolo, Ricci, Patrizia, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2019

Language:

english

File:

PDF, 13.50 MB

english, 2019

45

Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH

Carino, Adriana, Biagioli, Michele, Marchianò, Silvia, Fiorucci, Chiara, Zampella, Angela, Monti, Maria Chiara, Scarpelli, Paolo, Ricci, Patrizia, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2019

File:

PDF, 13.50 MB

2019

46

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

Biagioli, Michele, Carino, Adriana, Fiorucci, Chiara, Annunziato, Giannamaria, Marchianò, Silvia, Bordoni, Martina, Roselli, Rosalinda, Giorgio, Cristina Di, Castiglione, Federica, Ricci, Patrizia, Br

Journal:

Year:

2019

Language:

english

File:

PDF, 8.35 MB

english, 2019

47

Sa1518 – Mechanism of Acute Liver Decompensation Caused by Obeticholic Acid in Cholestasis is Fxr Dependent

Carino, Adriana, Biagioli, Michele, Marchianò, Silvia, Fiorucci, Chiara, Bordoni, Martina, Roselli, Rosalinda, Distrutti, Eleonora, Fiorucci, Stefano

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 155 KB

english, 2019

48

Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1

Biagioli, Michele, Carino, Adriana, MarchianÃ², Silvia, Roselli, Rosalinda, Di Giorgio, Cristina, Bordoni, Martina, Fiorucci, Chiara, Sepe, Valentina, Conflitti, Paolo, Limongelli, Vittorio, Distrutti

Journal:

Biochemical Pharmacology

Year:

2020

File:

PDF, 3.92 MB

2020